NASA C-BER integrates molecular biology, bioinformatics, bionanotechnology with chemical and biochemical analysis. Techniques for detecting, monitoring and controlling microorganisms are being developed; and the effects of microgravity, radiation and other space travel-induced stress factors on living organisms are investigated with the intent of developing countermeasures. The research of C-BER is closely aligned with NASA‘s Exploration Systems Mission Directorate and is relevant to all NASA‘s mission directorates. Our successes will improve existing technologies and generate new inventions that increase speed and accuracy while decreasing cost. New technology developed or advanced will educate and drive the perception of what is possible in the realm of Space Life Sciences. Historically, synergism between science and technology has thrived at TSU as applied to microgravity induced stress and microbial detection/control. In this current effort we will develop advanced technologies to enable novel solutions to the great health challenges facing humans during long-term space duration missions. Overall we shall develop a future workforce in STEM fields; improve TSU‘s research infrastructure and innovative partnerships; enhance astronaut and autonomous medical care; enhance technology transfers and commercialization; and improve quality of life on earth.